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Imidazopyrazines

In addition to the nitrogen-based heterocycles presented so far, a number of others nitrogen-based scaffolds have also been reported as promising agents for GBM treatment, including pyrazolo-triazole, imidazotetrazine, piperidine, purine, imidazopyrazine, pyrazole, triazole among others.

6-chloroimidazo[1,2-a]pyrazine

3-bromo-8-chloroimidazo[1,2-a]pyrazine

2-bromo-5H,6H,7H,8H-imidazo[1,2-a]pyrazine

3-bromo-5H,6H,7H,8H-imidazo[1,2-a]pyrazine dihydrochloride

3-bromo-8-chloro-2-methylimidazo[1,2-a]pyrazine

8-chloro-2-methylimidazo[1,2-a]pyrazine

3-bromo-8-(methylsulfanyl)imidazo[1,2-a]pyrazine

5-bromo-1H-imidazo[4,5-b]pyrazine

methyl imidazo[1,2-a]pyrazine-8-carboxylate

5-chloroimidazo[1,2-a]pyrazine

8-bromo-6-methylimidazo[1,2-a]pyrazine

3-bromo-5-methylimidazo[1,2-a]pyrazine

methyl 6-bromoimidazo[1,2-a]pyrazine-8-carboxylate

3-bromo-5-methoxyimidazo[1,2-a]pyrazine

6-bromo-8-methoxyimidazo[1,2-a]pyrazine

3-bromo-5-chloroimidazo[1,2-a]pyrazine

6-bromo-5-methylimidazo[1,2-a]pyrazine

6-bromo-8-methylimidazo[1,2-a]pyrazine

imidazo[1,2-a]pyrazin-3-amine hydrochloride

3-Bromo-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine Hydrochloride

ethyl 6,8-dibromoimidazo[1,2-a]pyrazine-2-carboxylate

ethyl 5-bromoimidazo[1,2-a]pyrazine-2-carboxylate

imidazo[1,5-a]pyrazine

1-bromo-3-methylimidazo[1,5-a]pyrazine