Produktname:2-(difluoromethoxy)acetic acid

IUPAC Name:2-(difluoromethoxy)acetic acid

CAS:1089695-61-3
Molekulare Formel:C3H4F2O3
Reinheit:95%+
Katalognummer:CM460686
Molekulargewicht:126.06

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Produkt-Details

CAS-Nr.:1089695-61-3
Molekulare Formel:C3H4F2O3
Schmelzpunkt:-
SMILES-Code:OC(=O)COC(F)F
Dichte:
Katalognummer:CM460686
Molekulargewicht:126.06
Siedepunkt:
Mdl-Nr.:MFCD28118272
Lagerung:

Column Infos

Deucrictibant
Pharvaris announced positive top-line data from the CHAPTER-1 Phase 2 clinical study meeting its primary endpoint, with deucrictibant demonstrating statistically significant and clinically meaningful results of deucrictibant as an oral preventative treatment for people living with HAE. The study's primary endpoint measured the time-standardized number of investigator-confirmed HAE episodes during treatment. Participants receiving 40 mg of deucrictibant daily had an 84.5% reduction in monthly exacerbation rates compared to placebo (p=0.0008). Deucrictibant is a potent, selective, and orally available antagonist of the bradykinin B2 receptor. By inhibiting bradykinin signaling through the bradykinin B2 receptor, deucrictibant has the potential to treat the clinical signs of an HAE attack and to prevent the occurrence of attacks.
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