Produktname:1-(3-(cyclopropylamino)quinoxalin-2-yl)piperidin-4-ol

IUPAC Name:1-[3-(cyclopropylamino)quinoxalin-2-yl]piperidin-4-ol

CAS:1146080-49-0
Molekulare Formel:C16H20N4O
Reinheit:95%
Katalognummer:CM142063
Molekulargewicht:284.36

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Produkt-Details

CAS-Nr.:1146080-49-0
Molekulare Formel:C16H20N4O
Schmelzpunkt:-
SMILES-Code:OC1CCN(C2=NC3=CC=CC=C3N=C2NC4CC4)CC1
Dichte:
Katalognummer:CM142063
Molekulargewicht:284.36
Siedepunkt:
Mdl-Nr.:MFCD11915930
Lagerung:

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Quinoxalines
Quinoxalines, also known as benzopyrazines, are heterocyclic compounds containing a ring complex consisting of a benzene ring and a pyrazine ring. It has isomerism with other naphthalene compounds such as quinazoline, phthalazine, cinnamine, etc. Fusion N-heterocyclic compounds are widely used as valuable entities for the expansion of important pharmacological agents and are considered to be an advantageous scaffold material. Among the numerous fused N-heterocyclic compounds, cinnoline, quinoxaline and quinazoline are important pharmacological agents. In medicinal chemistry, these N-heterocyclic compounds have a wide range of biological properties and can be used as synthetic intermediates, potential drug candidates and chemical probes.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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