Produktname:N-((1H-Indol-5-yl)methyl)cyclopropanamine hydrochloride

IUPAC Name:N-[(1H-indol-5-yl)methyl]cyclopropanamine hydrochloride

CAS:1158201-57-0
Molekulare Formel:C12H15ClN2
Reinheit:95%+
Katalognummer:CM229988
Molekulargewicht:222.72

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Produkt-Details

CAS-Nr.:1158201-57-0
Molekulare Formel:C12H15ClN2
Schmelzpunkt:-
SMILES-Code:[H]Cl.C1(NCC2=CC3=C(NC=C3)C=C2)CC1
Dichte:
Katalognummer:CM229988
Molekulargewicht:222.72
Siedepunkt:
Mdl-Nr.:MFCD09455733
Lagerung:

Category Infos

Indoles
Indole is a compound of pyrrole and benzene in parallel, also known as benzopyrrole. There are two combinations of pyrrole and benzene, called indole and isoindole, respectively. Many derivatives of indole have physiological and pharmacological activities, and can synthesize vasodilators, antihistamines, antipyretic analgesics, etc. in medicine, so indole is also a very important heterocyclic compound.
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Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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