cas 1177093-08-1|| where to buy 5-Cyclopropyl-3-(2-(piperazin-1-yl)pyrimidin-4-yl)-1,2,4-oxadiazole dihydrochloride

Produktname:5-Cyclopropyl-3-(2-(piperazin-1-yl)pyrimidin-4-yl)-1,2,4-oxadiazole dihydrochloride

IUPAC Name:4-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-(piperazin-1-yl)pyrimidine dihydrochloride

: CAS：1177093-08-1; Molekulare Formel：C13H18Cl2N6O; Reinheit：95%

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: CAS-Nr.:1177093-08-1; Molekulare Formel:C13H18Cl2N6O; Schmelzpunkt:-; SMILES-Code:[H]Cl.[H]Cl.C1(C2=NC(N3CCNCC3)=NC=C2)=NOC(C4CC4)=N1; Dichte:

: Katalognummer:CM309617; Molekulargewicht:345.23; Siedepunkt:; Mdl-Nr.:; Lagerung:Store at room temperature.

: Piperazines; Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.

: Pyrimidines; Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

: Oxadiazoles; Oxadiazoles are a class of heterocyclic aromatic compounds with the molecular formula C2H2N2O, which have special biological activities and thermodynamic properties. Five-membered heterocyclic moieties composed of three or two heteroatoms are of great interest to researchers because these compounds show significant therapeutic potential. These heterocycles can serve as a building block for the development of novel molecular structures.

: Cyclopropanes; Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.