Produktname:6-chloro-8-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazin-3-amine

IUPAC Name:6-chloro-8-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazin-3-amine

CAS:1178583-36-2
Molekulare Formel:C8H8ClN5
Reinheit:95%
Katalognummer:CM164460
Molekulargewicht:209.64

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Produkt-Details

CAS-Nr.:1178583-36-2
Molekulare Formel:C8H8ClN5
Schmelzpunkt:-
SMILES-Code:NC1=NN=C2C(C3CC3)=CC(Cl)=NN21
Dichte:
Katalognummer:CM164460
Molekulargewicht:209.64
Siedepunkt:
Mdl-Nr.:MFCD24644041
Lagerung:

Category Infos

Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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