Produktname:2-Chloro-5-(difluoromethoxy)pyrimidine
IUPAC Name:2-chloro-5-(difluoromethoxy)pyrimidine
- CAS:1192813-64-1
- Molekulare Formel:C5H3ClF2N2O
- Reinheit:95%+
- Katalognummer:CM325391
- Molekulargewicht:180.54
Nur für den Einsatz in Forschung und Entwicklung..
Produkt-Details
- CAS-Nr.:1192813-64-1
- Molekulare Formel:C5H3ClF2N2O
- Schmelzpunkt:-
- SMILES-Code:FC(F)OC1=CN=C(Cl)N=C1
- Dichte:
- Katalognummer:CM325391
- Molekulargewicht:180.54
- Siedepunkt:260.1±30.0°C at 760 mmHg
- Mdl-Nr.:MFCD18415615
- Lagerung:
Category Infos
- Pyrimidines
- Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Column Infos
- AZD0780
- AstraZeneca announced Phase I trial data for its PCSK9 inhibitor, AZD0780. AZD0780 is an oral small molecule PCSK9 inhibitor as a first-in-class therapy for patients with dyslipidemia that cannot be controlled by statins alone. PSCK9 is a well-known and validated target in lipid metabolism and inhibiting PSCK9 signalling has shown to be effective in reducing LDL cholesterol levels in plasma. Lower LDL-C levels are associated with a reduction in the risk of long-term cardiovascular disease and major cardiovascular events.
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.