Produktname:N-(2-((2,3-difluorobenzyl)thio)-6-(((2S,3R)-3,4-dihydroxybutan-2-yl)amino)pyrimidin-4-yl)azetidine-1-sulfonamide
IUPAC Name:N-(2-{[(2,3-difluorophenyl)methyl]sulfanyl}-6-{[(2S,3R)-3,4-dihydroxybutan-2-yl]amino}pyrimidin-4-yl)azetidine-1-sulfonamide
- CAS:1204707-73-2
- Molekulare Formel:C18H23F2N5O4S2
- Reinheit:98%
- Katalognummer:CM167694
- Molekulargewicht:475.53
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Produkt-Details
- CAS-Nr.:1204707-73-2
- Molekulare Formel:C18H23F2N5O4S2
- Schmelzpunkt:-
- SMILES-Code:O=S(N1CCC1)(NC2=NC(SCC3=CC=CC(F)=C3F)=NC(N[C@@H](C)[C@@H](O)CO)=C2)=O
- Dichte:
- Katalognummer:CM167694
- Molekulargewicht:475.53
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- Pyrimidines
- Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
- Azetidines
- Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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