Produktname:5-ethynyl-1H-pyrazolo[3,4-b]pyridine
IUPAC Name:5-ethynyl-1H-pyrazolo[3,4-b]pyridine
- CAS:1207351-15-2
- Molekulare Formel:C8H5N3
- Reinheit:95%
- Katalognummer:CM111790
- Molekulargewicht:143.15
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Produkt-Details
- CAS-Nr.:1207351-15-2
- Molekulare Formel:C8H5N3
- Schmelzpunkt:-
- SMILES-Code:C#CC1=CN=C(NN=C2)C2=C1
- Dichte:
- Katalognummer:CM111790
- Molekulargewicht:143.15
- Siedepunkt:
- Mdl-Nr.:MFCD22187975
- Lagerung:
Category Infos
- Pyrazolopyridines
- Over the past few years, many pyrazole fused-ring systems, especially with applications in medicinal chemistry, have been published. These include general structures such as pyrazoline, pyrazoline, pyrazoquinoline, pyrazoloisoquinoline, pyrazoline, pyrazolopyrazine, pyrazolopyrazine, pyranopyrazole, pyrano Pyrazoles, pyrazolotriazines and pyrazole fused phosphorus rings.
Column Infos
- Olverembatinib
- Ascentage Pharma announced that updated results from three studies of olverembatinib, have been released in posters at the 2024 European Hematology Association Hybrid Congress, taking place in Madrid, Spain.
Olverembatinib (HQP1351) is an oral, third-generation BCR-ABL1 tyrosine kinase inhibitor (TKI) developed by Ascentage Pharma for the treatment of chronic myeloid leukaemia (CML), acute myeloid leukaemia, acute lymphoblastic leukaemia (ALL) and solid tumours, including gastrointestinal stromal tumours (GIST). Olverembatinib is an ATP binding-site inhibitor of wild type BCR-ABL1 kinase and a broad spectrum of BCR-ABL1 mutants, including mutant T315I, which confers resistance against all first- and second-generation TKIs.