Produktname:4,5,6,7-tetradeuterio-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
IUPAC Name:2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro(²H₄)-1H-isoindole-1,3-dione
- CAS:1219177-18-0
- Molekulare Formel:C13H6D4N2O4
- Reinheit:95%+
- Katalognummer:CM340807
- Molekulargewicht:262.26
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Produkt-Details
- CAS-Nr.:1219177-18-0
- Molekulare Formel:C13H6D4N2O4
- Schmelzpunkt:-
- SMILES-Code:O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C([2H])=C([2H])C([2H])=C3[2H])=O
- Dichte:
- Katalognummer:CM340807
- Molekulargewicht:262.26
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- PROTAC-E3 Ligase Ligands
- Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
- PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.