Produktname:tert-butyl 4-(prop-2-yn-1-yloxy)piperidine-1-carboxylate

IUPAC Name:tert-butyl 4-(prop-2-yn-1-yloxy)piperidine-1-carboxylate

CAS:1219827-56-1
Molekulare Formel:C13H21NO3
Reinheit:95%+
Katalognummer:CM1046429
Molekulargewicht:239.32

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Produkt-Details

CAS-Nr.:1219827-56-1
Molekulare Formel:C13H21NO3
Schmelzpunkt:-
SMILES-Code:CC(C)(C)OC(=O)N1CCC(CC1)OCC#C
Dichte:
Katalognummer:CM1046429
Molekulargewicht:239.32
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
Piperidine,Piperidine Price
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Column Infos

KT-474
Kymera announced that the first patient has been dosed in the randomized Phase 2 clinical trial in hidradenitis suppurativa (HS) evaluating KT-474 (SAR444656). The Phase 2 study will evaluate the efficacy, safety, pharmacokinetics, and biological effects of KT-474 compared with placebo in adult patients with moderate to severe HS. Kymera's partner Sanofi is conducting the Phase 2 study in HS, and has initiated a second randomized Phase 2 trial in AD. Under the terms of the collaboration, dosing of the first patient in the HS trial generated a milestone payment of $40 million. KT-474 is an oral IRAK4 degrader, in development for the treatment of IL-1R/TLR-driven complex inflammatory diseases where there is an opportunity to significantly advance the standard of care, including HS and AD. Sanofi, which is collaborating with Kymera on the development of KT-474 outside of the oncology and immune-oncology fields, is conducting the Phase 2 studies.
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