Produktname:3-(4-(Tributylstannyl)thiazol-2-yl)oxetan-3-ol

IUPAC Name:3-[4-(tributylstannyl)-1,3-thiazol-2-yl]oxetan-3-ol

CAS:1245816-13-0
Molekulare Formel:C18H33NO2SSn
Reinheit:95%
Katalognummer:CM284084
Molekulargewicht:446.24

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Produkt-Details

CAS-Nr.:1245816-13-0
Molekulare Formel:C18H33NO2SSn
Schmelzpunkt:-
SMILES-Code:OC1(C2=NC([Sn](CCCC)(CCCC)CCCC)=CS2)COC1
Dichte:
Katalognummer:CM284084
Molekulargewicht:446.24
Siedepunkt:
Mdl-Nr.:MFCD16140389
Lagerung:

Category Infos

Thiazoles
Thiazoles are very important functional groups in medicinal chemistry. They act as ligands on a variety of biological matrices. Thiazoles are used in a wide range of therapeutic applications, such as antibacterial, antiretroviral, antifungal, antiallergic, antihypertensive, pain treatment, and to control symptoms of schizophrenia.
Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.