Produktname:6-Chloro-1H-pyrazolo[3,4-b]pyrazine

IUPAC Name:6-chloro-1H-pyrazolo[3,4-b]pyrazine

CAS:1260664-81-0
Molekulare Formel:C5H3ClN4
Reinheit:95%+
Katalognummer:CM248559
Molekulargewicht:154.56

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Produkt-Details

CAS-Nr.:1260664-81-0
Molekulare Formel:C5H3ClN4
Schmelzpunkt:-
SMILES-Code:ClC1=CN=C2C(NN=C2)=N1
Dichte:
Katalognummer:CM248559
Molekulargewicht:154.56
Siedepunkt:
Mdl-Nr.:MFCD18250166
Lagerung:Store at 2-8°C.

Category Infos

Pyrazoles
Pyrazoles are organic compounds of the general formula C3H3N2H. It is a five-membered heterocycle consisting of three carbon atoms and two adjacent nitrogen atoms. As an H-bond-donating heterocycle, pyrazole has been used as a more lipophilic and metabolically more stable bioisomer of phenol. Pyrazoles have attracted more and more attention due to their broad spectrum of action and strong efficacy.
Pyrazone
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Pyrazines
Pyrazine is a heterocyclic aromatic organic compound with chemical formula C4H4N2. The marketed pyrazine drugs are mainly distributed in the field of anti-tumor and anti-infection. In recent years, there have been many new drugs in various fields, and there are some new target drugs worthy of attention.
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Column Infos

GDC-1971
Protein tyrosine phosphatase SHP2 mediates RAS-driven MAPK signaling and has emerged in recent years as a target of interest in oncology, both for treating with a single agent and in combination with a KRAS inhibitor. GDC-1971 (formerly RLY-1971) is a SHP2 inhibitor currently in clinical trials in combination with KRAS G12C inhibitor divarasib (GDC-6036) for the treatment of solid tumors driven by a KRAS G12C mutation.