Produktname:6-hydroxy-2-azabicyclo[2.2.2]octane hydrochloride
IUPAC Name:2-azabicyclo[2.2.2]octan-6-ol hydrochloride
Product Overview |
6-Hydroxy-2-azabicyclo[2.2.2]octane hydrochloride, also known as 6-OHDA, is a chemical compound that is widely used in scientific research to study the nervous system. This compound is a potent neurotoxin that selectively destroys dopaminergic neurons, making it a valuable tool for investigating the mechanisms underlying Parkinson's disease and other neurological disorders. |
Synthesis Method |
The synthesis of 6-Hydroxy-2-azabicyclo[2.2.2]octane hydrochloride involves the oxidation of dopamine using hydrogen peroxide and iron salts. The resulting product is then purified and converted into its hydrochloride salt form. This synthesis method allows for the production of high-purity 6-Hydroxy-2-azabicyclo[2.2.2]octane hydrochloride that is suitable for use in scientific research. |
Chemical Properties |
6-Hydroxy-2-azabicyclo[2.2.2]octane hydrochloride is relatively easy to synthesize and can be produced in high-purity form for use in scientific research. This compound is highly toxic and can be dangerous to handle, requiring strict safety protocols to be followed. |
Synthesis and Application |
6-Hydroxy-2-azabicyclo[2.2.2]octane hydrochloride is commonly used in scientific research to study the nervous system and its functions. This compound is particularly useful in investigating the mechanisms underlying Parkinson's disease, as it selectively destroys dopaminergic neurons in the brain. This allows researchers to study the effects of dopamine depletion on the nervous system and develop new treatments for Parkinson's disease. |
Future Directions |
One area of interest is the development of new treatments for Parkinson's disease that target the mechanisms underlying dopamine depletion. Additionally, researchers may investigate the use of 6-Hydroxy-2-azabicyclo[2.2.2]octane hydrochloride in studying other neurological disorders, such as Alzheimer's disease and Huntington's disease. Finally, further research may be conducted to better understand the biochemical and physiological effects of 6-Hydroxy-2-azabicyclo[2.2.2]octane hydrochloride on the nervous system, providing valuable insights into the mechanisms underlying neurological disorders. |