Produktname:3-(4-Chlorophenyl)-1-oxa-3,7-diazaspiro[4.4]nonan-2-one

IUPAC Name:3-(4-chlorophenyl)-1-oxa-3,7-diazaspiro[4.4]nonan-2-one

CAS:1316219-88-1
Molekulare Formel:C12H13ClN2O2
Reinheit:97%
Katalognummer:CM207462
Molekulargewicht:252.7

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Produkt-Details

CAS-Nr.:1316219-88-1
Molekulare Formel:C12H13ClN2O2
Schmelzpunkt:-
SMILES-Code:O=C1OC2(CNCC2)CN1C3=CC=C(Cl)C=C3
Dichte:
Katalognummer:CM207462
Molekulargewicht:252.7
Siedepunkt:
Mdl-Nr.:MFCD18381641
Lagerung:

Category Infos

Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
Spiro And Bicyclic Compound
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Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
Oxazolidines
Oxazolidines are five-membered ring compounds consisting of three carbons, nitrogen and oxygen. Oxygen and nitrogen are in the 1 and 3 positions, respectively. Oxazolidine is in general yellow or slightly yellow, alkaline liquid or solid, easily hydrolyzed by water or alcohol. It is insoluble in water (or hydrolyzed); soluble in benzene and chloroform. Oxazolidine derivatives are five-membered cyclic compounds containing at least one oxygen and nitrogen in their molecular structure. Oxazolidine derivatives are known to possess various therapeutic activities, such as anticancer and antibiotic properties.

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