Produktname:propan-2-yl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonate
IUPAC Name:propan-2-yl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonate
- CAS:1324003-62-4
- Molekulare Formel:C15H23BO5S
- Reinheit:95%+
- Katalognummer:CM1045561
- Molekulargewicht:326.21
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Produkt-Details
- CAS-Nr.:1324003-62-4
- Molekulare Formel:C15H23BO5S
- Schmelzpunkt:-
- SMILES-Code:CC(C)OS(=O)(=O)C1=C(C=CC=C1)B1OC(C)(C)C(C)(C)O1
- Dichte:
- Katalognummer:CM1045561
- Molekulargewicht:326.21
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- Boronic Acids and Esters
- Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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Column Infos
- Sparsentan
- CSL Vifor and Travere Therapeutics announce European Commission approves FILSPARI(sparsentan) for the treatment of IgA Nephropathy (IgAN). First non-immunosuppressive therapy for the treatment of IgAN approved in Europe.
Sparsentan is a novel, non-immunosuppressive, single-molecule, dual endothelin angiotensin receptor antagonist with high selectivity for the endothelin A receptor (ETAR) and the angiotensin II subtype 1 receptor (AT1R). Pre-clinical data have shown that blockade of both endothelin type A and angiotensin II type 1 pathways in forms of rare chronic kidney disease, protects podocytes, prevents glomerulosclerosis and mesangial cell proliferation, and reduces proteinuria.