Produktname:Mal-amido-PEG8-C2-acid

IUPAC Name:1-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid

CAS:1334177-86-4
Molekulare Formel:C26H44N2O13
Reinheit:95%+
Katalognummer:CM198697
Molekulargewicht:592.64

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Produkt-Details

CAS-Nr.:1334177-86-4
Molekulare Formel:C26H44N2O13
Schmelzpunkt:-
SMILES-Code:O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O
Dichte:
Katalognummer:CM198697
Molekulargewicht:592.64
Siedepunkt:747.9±60.0°C at 760 mmHg
Mdl-Nr.:
Lagerung:Store at room temperature.

Category Infos

Pyrrolines
Pyrrolines, also called dihydropyrroles, are obtained from aromatic pyrroles by hydrogenation. 1-pyrroline is a cyclic imine, while 2-pyrroline and 3-pyrroline are cyclic amines.
ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
PEG linkers
PEG Reagents are chemically functionalized polyethylene glycol (PEG) linkers.PEG linkers are highly water-soluble and non-immunogenic linkers.
Maleimides
Thiol-maleimide is a bifunctional chemical compound that is commonly used in bioconjugation reactions to crosslink two molecules via the thiol (-SH) groups.
Non-cleavable linkers
Noncleavable linkers consist of stable bonds that resist proteolytic degradation and provide higher stability than the cleavable linkers.

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