Produktname:2-(azetidin-3-yloxy)-3-chloro-5-(trifluoromethyl)pyridine
IUPAC Name:2-(azetidin-3-yloxy)-3-chloro-5-(trifluoromethyl)pyridine
- CAS:1343197-07-8
- Molekulare Formel:C9H8ClF3N2O
- Reinheit:95%+
- Katalognummer:CM570608
- Molekulargewicht:252.62
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Produkt-Details
- CAS-Nr.:1343197-07-8
- Molekulare Formel:C9H8ClF3N2O
- Schmelzpunkt:-
- SMILES-Code:FC(F)(F)C1=CN=C(OC2CNC2)C(Cl)=C1
- Dichte:
- Katalognummer:CM570608
- Molekulargewicht:252.62
- Siedepunkt:
- Mdl-Nr.:MFCD18267829
- Lagerung:
Category Infos
- Pyridines
- Pyridine is a six-membered heterocyclic compound containing one nitrogen heteroatom. Pyridine and piperidine are the most frequently occurring heterocyclic building blocks in drug molecules. According to incomplete statistics, there are currently more than 180 drugs containing pyridine or piperidine structure that have been marketed, nearly 1/5 of the drugs approved for marketing in recent years contain these two structures.
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- Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell.
- Fluorinated Compounds
- Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
- Azetidines
- Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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