Produktname:2-Amino-7-(1-hydroxypropan-2-yl)-1H-purin-6(7H)-one

IUPAC Name:2-amino-7-(1-hydroxypropan-2-yl)-6,7-dihydro-1H-purin-6-one

CAS:1346603-33-5
Molekulare Formel:C8H11N5O2
Reinheit:97%
Katalognummer:CM236390
Molekulargewicht:209.21

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Produkt-Details

CAS-Nr.:1346603-33-5
Molekulare Formel:C8H11N5O2
Schmelzpunkt:-
SMILES-Code:NC(N1)=NC(N=CN2C(C)CO)=C2C1=O
Dichte:
Katalognummer:CM236390
Molekulargewicht:209.21
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

Purines
Purines are heterocyclic aromatic compounds composed of linked pyrimidine and imidazole rings. In mammals, purines are most commonly expressed in DNA and RNA (including the purines adenine and guanine), as well as single-molecule nucleotides (adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP), cyclic AMP, and to a lesser extent guanosine triphosphate (GTP) and cyclic guanosine monophosphate (cGMP). Purines are also key elements of the following energy metabolism molecules: reduced nicotinamide adenine dinucleotide, nicotinamide adenine dinucleotide phosphate (NADPH), and coenzyme Q. Purines can also act as direct neurotransmitters; for example, adenosine may interact with receptors to modulate cardiovascular and central nervous system (CNS) function.
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Product Other Information

Product Overview 7-(1-Methyl-2-hydroxyethyl)guanine, also known as MheG, is a modified nucleoside that has been found to have potential applications in scientific research.
Synthesis Method 7-(1-Methyl-2-hydroxyethyl)guanine is synthesized through a multistep process that involves the reaction of guanine with formaldehyde and sodium cyanoborohydride. The resulting compound is then treated with methyl iodide and hydroxide to form 7-(1-Methyl-2-hydroxyethyl)guanine. This synthesis method has been optimized to produce high yields of 7-(1-Methyl-2-hydroxyethyl)guanine with minimal impurities.
Chemical Properties 7-(1-Methyl-2-hydroxyethyl)guanine has some limitations, including its potential toxicity and the difficulty of synthesizing large quantities of pure 7-(1-Methyl-2-hydroxyethyl)guanine.
Synthesis and Application This compound has been found to have unique properties that make it useful for studying the structure and function of nucleic acids. For example, 7-(1-Methyl-2-hydroxyethyl)guanine has been used as a probe to study the structure of DNA and RNA, as well as to investigate the interactions between nucleic acids and proteins.
Future Directions One area of interest is the development of new synthetic methods for producing 7-(1-Methyl-2-hydroxyethyl)guanine with higher yields and purity. Another potential direction is the investigation of the therapeutic potential of 7-(1-Methyl-2-hydroxyethyl)guanine in cancer treatment, particularly in combination with other drugs. Additionally, further studies are needed to fully understand the mechanism of action of 7-(1-Methyl-2-hydroxyethyl)guanine and its effects on gene expression and other cellular processes.