Produktname:(1S,3S,4R)-Ethyl2-((R)-1-phenylethyl)-2-azabicyclo[2.2.2]oct-5-ene-3-carboxylate

IUPAC Name:ethyl (1S,3S,4R)-2-[(1R)-1-phenylethyl]-2-azabicyclo[2.2.2]oct-5-ene-3-carboxylate

CAS:134984-64-8
Molekulare Formel:C18H23NO2
Reinheit:97%
Katalognummer:CM494928
Molekulargewicht:285.39

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Produkt-Details

CAS-Nr.:134984-64-8
Molekulare Formel:C18H23NO2
Schmelzpunkt:-
SMILES-Code:O=C([C@H]1N([C@@H](C2=CC=CC=C2)C)[C@]3([H])C=C[C@@]1([H])CC3)OCC
Dichte:
Katalognummer:CM494928
Molekulargewicht:285.39
Siedepunkt:
Mdl-Nr.:MFCD27978833
Lagerung:

Column Infos

DSP-5336
Sumitomo Pharma announces that DSP-5336 has received FDA Fast Track Designation for the treatment of relapsed or refractory acute myeloid leukemia (AML) with a KMT2A rearrangement, also known as, mixed lineage leukemia rearrangement (MLLr) or nucleophosmin mutation (NPM1m). Menin serves as a tumor suppressor in endocrine glands. Novel menin inhibitors are novel targeted agents in clinical studies targeting genetically defined subsets of acute leukemia.
DSP-5336 is an investigational menin-MLL interaction inhibitor. DSP-5336 has been granted Orphan Drug Designation in acute myeloid leukemia, and Fast Track Designation in relapsed or refractory acute myeloid leukemia with MLLr or NPM1m.

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