Produktname:8-Chloro-2-phenyl-3-((1S)-1-((9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)amino)ethyl)isoquinolin-1(2H)-one

IUPAC Name:8-chloro-3-[(1S)-1-{[9-(oxan-2-yl)-9H-purin-6-yl]amino}ethyl]-2-phenyl-1,2-dihydroisoquinolin-1-one

CAS:1350643-73-0
Molekulare Formel:C27H25ClN6O2
Reinheit:95%+
Katalognummer:CM330642
Molekulargewicht:500.98

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Produkt-Details

CAS-Nr.:1350643-73-0
Molekulare Formel:C27H25ClN6O2
Schmelzpunkt:-
SMILES-Code:ClC1=C(C2=O)C(C=C([C@@H](NC3=NC=NC4=C3N=CN4C5OCCCC5)C)N2C6=CC=CC=C6)=CC=C1
Dichte:
Katalognummer:CM330642
Molekulargewicht:500.98
Siedepunkt:
Mdl-Nr.:
Lagerung:Store at room temperature

Category Infos

Imidazoles
Imidazole is an important five-membered nitrogen-containing heterocyclic compound. Among the numerous heterocyclic compounds, imidazole and its derivatives are regarded as a unique and multifaceted scaffold material due to their diverse applications in industrial, organic and pharmaceutical chemistry. Imidazoles interact in different ways with many therapeutic targets, enzymes and receptors in biological systems and thus exhibit a wide range of biological activities. In particular, several imidazoles can be used as clinical drugs to treat various types of cancer with high therapeutic efficacy. Furthermore, imidazoles are one of the most critical segments in the field of anti-covid-19 virus drug discovery due to their ability to interact with active targets in living systems.
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Purines
Purines are heterocyclic aromatic compounds composed of linked pyrimidine and imidazole rings. In mammals, purines are most commonly expressed in DNA and RNA (including the purines adenine and guanine), as well as single-molecule nucleotides (adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP), cyclic AMP, and to a lesser extent guanosine triphosphate (GTP) and cyclic guanosine monophosphate (cGMP). Purines are also key elements of the following energy metabolism molecules: reduced nicotinamide adenine dinucleotide, nicotinamide adenine dinucleotide phosphate (NADPH), and coenzyme Q. Purines can also act as direct neurotransmitters; for example, adenosine may interact with receptors to modulate cardiovascular and central nervous system (CNS) function.
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Isoquinolines
Compared to quinolines, isoquinolines are also prominent structural motifs present in many biologically significant natural and synthetic compounds. Some well-known isoquinoline alkaloids include the anticancer and anticonvulsant berberine, the vasodilator and antispasmodic drugs papaverine and emetine. In addition to naturally occurring isoquinolines, synthetic analogs have also shown significant biological activity.
Tetrahydropyrans
Tetrahydropyran is an organic compound consisting of a saturated six-membered ring containing five carbon atoms and one oxygen atom. Tetrahydropyrans are common structural motifs in natural products and synthetic therapeutic molecules. In nature, these six-membered oxygen heterocycles are usually assembled by intramolecular reactions, including oxygen Michael addition or ring opening of epoxy alcohols. In fact, polyether natural products have been particularly extensively studied for their fascinating structures and important biological properties; these are often formed through endoselective epoxy open cascades.