Produktname:DBCO-NHS ester

IUPAC Name:2,5-dioxopyrrolidin-1-yl 4-{2-azatricyclo[10.4.0.0⁴,⁹]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-4-oxobutanoate

CAS:1353016-71-3
Molekulare Formel:C23H18N2O5
Reinheit:95%+
Katalognummer:CM338888
Molekulargewicht:402.41

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Produkt-Details

CAS-Nr.:1353016-71-3
Molekulare Formel:C23H18N2O5
Schmelzpunkt:-
SMILES-Code:O=C(N1CC2=CC=CC=C2C#CC3=CC=CC=C31)CCC(ON4C(CCC4=O)=O)=O
Dichte:
Katalognummer:CM338888
Molekulargewicht:402.41
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
N-Hydroxysuccinimide (NHS)
N-Hydroxysuccinimide
Alkynes
Alkynes are unsaturated hydrocarbons containing at least one carbon—carbon triple bond.
Non-cleavable linkers
Noncleavable linkers consist of stable bonds that resist proteolytic degradation and provide higher stability than the cleavable linkers.

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