Produktname:2,4-dichloro-5-iodopyrimidine

IUPAC Name:2,4-dichloro-5-iodopyrimidine

CAS:13544-44-0
Molekulare Formel:C4HCl2IN2
Reinheit:95%+
Katalognummer:CM112286
Molekulargewicht:274.87

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Produkt-Details

CAS-Nr.:13544-44-0
Molekulare Formel:C4HCl2IN2
Schmelzpunkt:-
SMILES-Code:IC1=CN=C(Cl)N=C1Cl
Dichte:
Katalognummer:CM112286
Molekulargewicht:274.87
Siedepunkt:
Mdl-Nr.:MFCD01898087
Lagerung:

Category Infos

Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

Column Infos

INX-315
Incyclix Bio announces FDA clearance of investigational new drug application for INX-315 in patients with advanced or metastatic cancer. INX-315 is a novel, potent and selective inhibitor of Cyclin-dependent kinase 2 (CDK2) with compelling pre-clinical efficacy and safety data.
CDK2 is thought to play an important role in driving proliferation of certain cancers, including those harboring CCNE1 amplification and breast cancers that have acquired resistance to CDK4/6 inhibitors (CDK4/6i).