Produktname:(3-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoxazol-5-yl)methyl acetate
IUPAC Name:[3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-oxazol-5-yl]methyl acetate
- CAS：1380089-34-8
- Molekulare Formel：C13H20BNO5
- Reinheit：97%
- Katalognummer：CM208606
- Molekulargewicht：281.12
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Produkt-Details
- CAS-Nr.:1380089-34-8
- Molekulare Formel:C13H20BNO5
- Schmelzpunkt:-
- SMILES-Code:CC(OCC1=C(B2OC(C)(C)C(C)(C)O2)C(C)=NO1)=O
- Dichte:
- Katalognummer:CM208606
- Molekulargewicht:281.12
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- Boronic Acids and Esters
- Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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- Find trusted boronic acid for sale. Any requirements and problems can ask us at any time.
- Isoxazoles
- Isoxazole is a liquid heterocyclic compound C3H3NO isomeric with oxazole and having a penetrating odor like that of pyridine. Isoxazoles belong to an important class of five-membered aromatic heterocycles containing two electronegative heteroatoms, nitrogen and oxygen, in a 1,2-relationship and three regular sp2 carbon atoms. These molecules are found to be key components in various synthetic products in daily use and also present as a pharmacophore essential for biological activity in many drugs and bioactive natural products. In addition, isoxazoles have demonstrated their ability to exhibit hydrogen bond donor/acceptor interactions with a variety of enzymes and receptors.
Column Infos
- Pelabresib
- MorphoSys’ phase 3 study of Pelabresib in myelofibrosis demonstrates statistically significant improvement in spleen volume reduction and strong positive trend in symptom reduction.
Pelabresib (CPI-0610) is an investigational selective small molecule designed to promote anti-tumor activity by inhibiting the function of bromodomain and extra-terminal domain (BET) proteins to decrease the expression of abnormally expressed genes in cancer. MorphoSys intends to submit for approval in the U.S. and Europe in mid-2024.
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