Produktname:4-(2-Chloro-6-(tetrahydro-2H-pyran-4-yl)pyrimidin-4-yl)morpholine

IUPAC Name:4-[2-chloro-6-(oxan-4-yl)pyrimidin-4-yl]morpholine

CAS:1415562-55-8
Molekulare Formel:C13H18ClN3O2
Reinheit:95%+
Katalognummer:CM337250
Molekulargewicht:283.76

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Produkt-Details

CAS-Nr.:1415562-55-8
Molekulare Formel:C13H18ClN3O2
Schmelzpunkt:-
SMILES-Code:ClC1=NC(C2CCOCC2)=CC(N3CCOCC3)=N1
Dichte:
Katalognummer:CM337250
Molekulargewicht:283.76
Siedepunkt:
Mdl-Nr.:
Lagerung:-20ºC

Category Infos

Morpholines
Morpholine contains secondary amine groups and has all the typical reactive characteristics of secondary amine groups. It can react with inorganic acids to form salts, and react with organic acids to form salts or amides, which can be subjected to alkylation reaction, and can also be reacted with ethylene oxide, ketone or Willgerodt reaction. Morpholine is a six-membered ring containing oxygen and nitrogen, and its alkalinity is much lower than that of its parent piperidine. The marketed morpholine drugs are mainly distributed in the fields of tumors, cardiovascular and cerebrovascular diseases, respiratory system diseases, digestive system diseases, infectious diseases and mental disorders.
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Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Tetrahydropyrans
Tetrahydropyran is an organic compound consisting of a saturated six-membered ring containing five carbon atoms and one oxygen atom. Tetrahydropyrans are common structural motifs in natural products and synthetic therapeutic molecules. In nature, these six-membered oxygen heterocycles are usually assembled by intramolecular reactions, including oxygen Michael addition or ring opening of epoxy alcohols. In fact, polyether natural products have been particularly extensively studied for their fascinating structures and important biological properties; these are often formed through endoselective epoxy open cascades.

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