Produktname:3-(6-hydroxy-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione

IUPAC Name:3-(5-hydroxy-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione

CAS:1416990-08-3
Molekulare Formel:C13H12N2O4
Reinheit:95%+
Katalognummer:CM338819
Molekulargewicht:260.25

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Produkt-Details

CAS-Nr.:1416990-08-3
Molekulare Formel:C13H12N2O4
Schmelzpunkt:-
SMILES-Code:O=C(C(N1CC2=C(C=CC(O)=C2)C1=O)CC3)NC3=O
Dichte:
Katalognummer:CM338819
Molekulargewicht:260.25
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.

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