Produktname:(S)-3-(Pyrrolidin-3-yl)-2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridine

IUPAC Name:(3S)-3-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine

CAS:1417789-01-5
Molekulare Formel:C11H11F3N4
Reinheit:95%
Katalognummer:CM151151
Molekulargewicht:256.23

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Produkt-Details

CAS-Nr.:1417789-01-5
Molekulare Formel:C11H11F3N4
Schmelzpunkt:-
SMILES-Code:FC(C1=NC2=CC=CN=C2N1[C@@H]3CNCC3)(F)F
Dichte:
Katalognummer:CM151151
Molekulargewicht:256.23
Siedepunkt:
Mdl-Nr.:MFCD22631751
Lagerung:

Category Infos

Imidazopyridines
With four imidazopyridine-containing drugs and one pyrazolopyridine-containing drug on the market, bicyclic pyridines containing ring-junction nitrogen are privileged structures in medicinal chemistry. With two nitrogen atoms with potential to serve as hydrogen bond acceptors, imidazopyridines and pyrazolopyridines may boost binding to target proteins and elevate potency. In addition, these structures have found utility in FBDD, covalent inhibitors, reducing metabolic liabilities, and creating novel chemical space and intellectual properties. With many of the advanced intermediates now commercially available, they will find more and more applications in drug discovery.
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Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.

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