Produktname:Cyclooctyne-O-NHS ester

IUPAC Name:2,5-dioxopyrrolidin-1-yl 2-(cyclooct-2-yn-1-yloxy)acetate

CAS:1425803-45-7
Molekulare Formel:C14H17NO5
Reinheit:95%+
Katalognummer:CM338904
Molekulargewicht:279.29

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Produkt-Details

CAS-Nr.:1425803-45-7
Molekulare Formel:C14H17NO5
Schmelzpunkt:-
SMILES-Code:O=C(ON1C(CCC1=O)=O)COC2C#CCCCCC2
Dichte:
Katalognummer:CM338904
Molekulargewicht:279.29
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
N-Hydroxysuccinimide (NHS)
N-Hydroxysuccinimide
Non-cleavable linkers
Noncleavable linkers consist of stable bonds that resist proteolytic degradation and provide higher stability than the cleavable linkers.

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