cas 1431698-03-1|| where to buy N-propyl-3-(1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-5-yl)imidazo[1,2-b]pyridazin-6-amine

Produktname:N-propyl-3-(1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-5-yl)imidazo[1,2-b]pyridazin-6-amine

IUPAC Name:3-[1-(oxan-2-yl)-1H-indazol-5-yl]-N-propylimidazo[1,2-b]pyridazin-6-amine

Packungseinheit	Verfügbarer Vorrat	Preis($)
CM330788-100mg	in stock	ŁŁƏ
CM330788-250mg	in stock	ǎĜǭ
CM330788-1g	1-2 Weeks	ƩŽƏţ

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: CAS-Nr.:1431698-03-1; Molekulare Formel:C21H24N6O; Schmelzpunkt:-; SMILES-Code:CCCNC(C=C1)=NN2C1=NC=C2C3=CC4=C(N(C5CCCCO5)N=C4)C=C3; Dichte:

: Katalognummer:CM330788; Molekulargewicht:376.45; Siedepunkt:; Mdl-Nr.:; Lagerung:2-8°C

: Indazoles; Indazoles are a class of organic heterocyclic compounds, also known as 1,2-diazaindene and benzopyrazole. Indazole is a good bioisomer of phenol, which is more lipophilic than phenol and less prone to phase I and II metabolism. Indazole derivatives have a wide range of biological activities, and it has been confirmed that indazole compounds have anti-tumor, analgesic, anti-inflammatory and other drug activities. Anticancer is the most important application field of indazole drugs. Renal cell carcinoma, solid tumor, nausea and vomiting caused by chemotherapy and leukemia are the main indications of this structural backbone drug.

: Tetrahydropyrans; Tetrahydropyran is an organic compound consisting of a saturated six-membered ring containing five carbon atoms and one oxygen atom. Tetrahydropyrans are common structural motifs in natural products and synthetic therapeutic molecules. In nature, these six-membered oxygen heterocycles are usually assembled by intramolecular reactions, including oxygen Michael addition or ring opening of epoxy alcohols. In fact, polyether natural products have been particularly extensively studied for their fascinating structures and important biological properties; these are often formed through endoselective epoxy open cascades.

: Imidazopyridazines; Potent IRAK-4 inhibitors have been reported by several groups including some structurally related benzimidazoles as well as alternative fused heterocycles such as the imidazopyridine and imidazopyridazine. Such compounds are reported to have IRAK-1 and IRAK-4 activity with varying degrees of selectivity.