Produktname:8-tert-Butyl 4-ethyl 3-oxo-2,8-diazaspiro[4.5]decane-4,8-dicarboxylate

IUPAC Name:8-tert-butyl 4-ethyl 3-oxo-2,8-diazaspiro[4.5]decane-4,8-dicarboxylate

CAS:1445951-68-7
Molekulare Formel:C16H26N2O5
Reinheit:97%
Katalognummer:CM209749
Molekulargewicht:326.39

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Produkt-Details

CAS-Nr.:1445951-68-7
Molekulare Formel:C16H26N2O5
Schmelzpunkt:-
SMILES-Code:O=C(C1C(NCC12CCN(C(OC(C)(C)C)=O)CC2)=O)OCC
Dichte:
Katalognummer:CM209749
Molekulargewicht:326.39
Siedepunkt:
Mdl-Nr.:MFCD25509372
Lagerung:

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
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Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.

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Product Other Information

Product Overview 8-Tert-butyl 4-ethyl 3-oxo-2,8-diazaspiro[4.5]decane-4,8-dicarboxylate is a chemical compound that has gained significant attention in the scientific community due to its potential applications in various fields. It is a spirocyclic compound that belongs to the family of diazaspiro compounds, which are known for their biological activities. 
Synthesis Method The synthesis of 8-Tert-butyl 4-ethyl 3-oxo-2,8-diazaspiro[4.5]decane-4,8-dicarboxylate involves the reaction of tert-butyl 4-ethyl-1,2,3,6-tetrahydropyridine-3-carboxylate with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone in the presence of triethylamine. The reaction proceeds through a spirocyclization mechanism, forming the desired spirocyclic compound in moderate to good yield.
Physical Properties One limitation of using this compound in lab experiments is its relatively low solubility in water, which may make it difficult to work with in certain assays.
Synthesis and Application 8-Tert-butyl 4-ethyl 3-oxo-2,8-diazaspiro[4.5]decane-4,8-dicarboxylate has been found to have potential applications in various fields of scientific research. It has been studied for its antibacterial, antifungal, and antiviral activities. It has also been found to have potential as a therapeutic agent for the treatment of cancer, Alzheimer's disease, and Parkinson's disease.
Future Directions One direction is to further explore its potential as a therapeutic agent for various diseases, including cancer, Alzheimer's disease, and Parkinson's disease. Another direction is to investigate its mechanism of action in more detail, which may lead to the development of more effective drugs. Additionally, further studies are needed to determine the optimal conditions for using this compound in lab experiments, as well as its potential toxicity and side effects.