Produktname:(2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)pyrimidin-5-yl)boronic acid

IUPAC Name:(2-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}pyrimidin-5-yl)boronic acid

CAS:1448461-87-7
Molekulare Formel:C13H21BN4O4
Reinheit:95%
Katalognummer:CM135149
Molekulargewicht:308.15

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Produkt-Details

CAS-Nr.:1448461-87-7
Molekulare Formel:C13H21BN4O4
Schmelzpunkt:-
SMILES-Code:O=C(N1CCN(C2=NC=C(B(O)O)C=N2)CC1)OC(C)(C)C
Dichte:
Katalognummer:CM135149
Molekulargewicht:308.15
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

Piperazines
Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.
Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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