Produktname:2-Chloro-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one
IUPAC Name:2-chloro-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one
- CAS:1449598-86-0
- Molekulare Formel:C8H4ClFN2O
- Reinheit:95%+
- Katalognummer:CM337294
- Molekulargewicht:198.58
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Produkt-Details
- CAS-Nr.:1449598-86-0
- Molekulare Formel:C8H4ClFN2O
- Schmelzpunkt:-
- SMILES-Code:O=C1C=C(Cl)N=C2N1C=C(F)C=C2
- Dichte:
- Katalognummer:CM337294
- Molekulargewicht:198.58
- Siedepunkt:
- Mdl-Nr.:MFCD28659052
- Lagerung:
Column Infos
- Risdiplam
- As the first approved small molecule splicing modifier drug, Risdiplam (Evrysdi) is granted approval by the European Commission to expand the EU marketing authorization. This extension now includes infants with a clinical diagnosis of SMA Type 1, Type 2 or Type 3 or with one to four SMN2 copies from birth to below two months. Type 1 spinal muscular atrophy (SMA) is a rare, progressive neuromuscular disease and a leading genetic factor of infant mortality, that is caused by low levels of functional survival of motor neuron (SMN) protein. Risdiplam modifies SMN2 pre-messenger RNA splicing and increases levels of functional SMN protein in both the central nervous system and peripheral organs.