cas 1454847-99-4|| where to buy methyl 2-[(1R)-1-(2-aminopyridin-3-yl)oxyethyl]-4-fluorobenzoate

Produktname:methyl 2-[(1R)-1-(2-aminopyridin-3-yl)oxyethyl]-4-fluorobenzoate

IUPAC Name:methyl 2-[(1R)-1-[(2-aminopyridin-3-yl)oxy]ethyl]-4-fluorobenzoate

: CAS：1454847-99-4; Molekulare Formel：C15H15FN2O3; Reinheit：95%+

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CM336707-100mg	in stock	ſƋǠ
CM336707-250mg	in stock	ǲƋƋ

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: CAS-Nr.:1454847-99-4; Molekulare Formel:C15H15FN2O3; Schmelzpunkt:-; SMILES-Code:O=C(OC)C1=CC=C(F)C=C1[C@H](OC2=CC=CN=C2N)C; Dichte:

: Katalognummer:CM336707; Molekulargewicht:290.29; Siedepunkt:; Mdl-Nr.:; Lagerung:

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: Lorlatinib; Pfizer announced longer-term follow-up results of the Phase 3 CROWN study at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting. This study aims to evaluate the efficacy and safety of the third-generation anaplastic lymphoma kinase (ALK) inhibitor LORBRENA® (lorlatinib, available in Europe under the brand name LORVIQUA®) versus XALKORI® (crizotinib) in people with previously untreated, anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC). The analysis showed that compared with the first-generation ALK inhibitors, the risk of disease progression or death in patients treated with lorlatinib continued to decrease by 81%, and the risk of brain metastasis progression was reduced by 94%.