Produktname:tert-butyl4-bromo-3,5-dimethyl-2,6-dioxo-3,6-dihydropyrimidine-1(2H)-carboxylate

IUPAC Name:tert-butyl 4-bromo-3,5-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-1-carboxylate

CAS:1643462-61-6
Molekulare Formel:C11H15BrN2O4
Reinheit:95%+
Katalognummer:CM336709
Molekulargewicht:319.16

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Produkt-Details

CAS-Nr.:1643462-61-6
Molekulare Formel:C11H15BrN2O4
Schmelzpunkt:-
SMILES-Code:O=C(N(C(N(C)C(Br)=C1C)=O)C1=O)OC(C)(C)C
Dichte:
Katalognummer:CM336709
Molekulargewicht:319.16
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

Column Infos

Tavapadon
Cerevel Therapeutics announces positive topline results for Tavapadon in phase 3 adjunctive trial for people living with Parkinson’s disease. The TEMPO-3 trial evaluated its efficacy, safety and tolerability met the primary endpoint and key secondary endpoint. The neurotransmitter dopamine is linked to working memory and motor movement, and the loss of dopamine-producing neurons in the brain result in Parkinson’s disease.
Tavapadon is a selective dopamine D1/D5 receptor partial agonist for the improved motor control. While most dopamine agonists target and stimulate D2/D3 dopamine receptors, Tavapadon is the only D1/D5 selective partial agonist in clinical development for PD.