Produktname:8-Chloro-2-(methylthio)pyrimido[5,4-d]pyrimidine
IUPAC Name:8-chloro-2-(methylsulfanyl)pyrimido[5,4-d][1,3]diazine
- CAS:176637-10-8
- Molekulare Formel:C7H5ClN4S
- Reinheit:95%+
- Katalognummer:CM167362
- Molekulargewicht:212.66
Nur für den Einsatz in Forschung und Entwicklung..
Produkt-Details
- CAS-Nr.:176637-10-8
- Molekulare Formel:C7H5ClN4S
- Schmelzpunkt:-
- SMILES-Code:CSC1=NC=C(N=CN=C2Cl)C2=N1
- Dichte:
- Katalognummer:CM167362
- Molekulargewicht:212.66
- Siedepunkt:
- Mdl-Nr.:MFCD00227587
- Lagerung:Store at 2-8°C.
Column Infos
- Zongertinib
- Boehringer’s zongertinib shows encouraging efficacy and tolerability profile in previously treated HER2 mutated lung cancer patients.
Zongertinib (also known as BI 1810631) is an investigational oral HER2-specific tyrosine kinase inhibitor (TKI) that is being developed as a potential treatment for HER2 mutated non-small cell lung cancer (NSCLC). Zongertinib was granted FDA Fast Track Designation in 2023, then in 2024 it was granted Breakthrough Therapy Designation by the U.S. FDA and China CDE for the treatment of adult patients with advanced NSCLC whose tumors have activating HER2 mutations, and who have received a prior systemic therapy.