Produktname:3-Cyclopropylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid

IUPAC Name:3-cyclopropylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid

CAS:1779124-35-4
Molekulare Formel:C10H9N3O2
Reinheit:95%+
Katalognummer:CM271710
Molekulargewicht:203.2

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Produkt-Details

CAS-Nr.:1779124-35-4
Molekulare Formel:C10H9N3O2
Schmelzpunkt:-
SMILES-Code:O=C(C1=CN2C(N=C1)=C(C3CC3)C=N2)O
Dichte:
Katalognummer:CM271710
Molekulargewicht:203.2
Siedepunkt:
Mdl-Nr.:MFCD26097160
Lagerung:

Category Infos

Pyrazolopyrimidines
Pyrazolopyrimidine scaffolds are one of the most important heterocyclic compounds in drug discovery. This scaffold has various biological activities, among which anticancer is an important one.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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Product Other Information

Product Overview 3-Cyclopropylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CPPCA) is a heterocyclic compound with a wide range of applications in the field of synthetic organic chemistry. CPPCA is a versatile building block for a variety of synthetic processes, including ring-closing metathesis, palladium-catalyzed cross-coupling reactions, and the synthesis of heterocyclic compounds. It is also used as a starting material for the synthesis of pharmaceuticals, agrochemicals, and other bioactive compounds. In addition, CPPCA has been used as a catalyst in the synthesis of polymers and other materials.
Synthesis and Application 3-Cyclopropylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid can be synthesized from a variety of starting materials, including cyclopropylpyrazole, cyclopropylpyrimidine, and cyclopropylpyrazinone. The most common and efficient method for the synthesis of 3-Cyclopropylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid is the reaction of cyclopropylpyrazole with ethyl chloroformate in the presence of a base, such as triethylamine. The reaction is carried out at room temperature and the product is isolated in high yield. Other methods for the synthesis of 3-Cyclopropylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid include the reaction of cyclopropylpyrazole with ethyl chloroformate in the presence of a base, such as triethylamine, and the reaction of cyclopropylpyrazole with ethyl chloroformate in the presence of a base, such as triethylamine. 3-Cyclopropylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid has been used in a variety of scientific research applications. For example, it has been used as a catalyst in the synthesis of polymers and other materials. In addition, 3-Cyclopropylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid has been used to synthesize heterocyclic compounds, such as pyridazines and pyrazolines, which have potential applications in medicinal chemistry. 3-Cyclopropylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid has also been used in the synthesis of pharmaceuticals, agrochemicals, and other bioactive compounds.
Future Directions The potential applications of 3-Cyclopropylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid are vast and varied, and there are many future directions for research. These include the development of new methods for the synthesis of 3-Cyclopropylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid, the exploration of its biochemical and physiological effects, and the investigation of its potential applications in medicinal chemistry. In addition, 3-Cyclopropylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid could be used as a starting material for the synthesis of polymers and other materials. Finally, 3-Cyclopropylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid could be used as a catalyst for the synthesis of heterocyclic compounds with potential applications in medicinal chemistry.