Produktname:7-(Trifluoromethyl)-3-azabicyclo[4.1.0]heptane

IUPAC Name:7-(trifluoromethyl)-3-azabicyclo[4.1.0]heptane

CAS:1780746-82-8
Molekulare Formel:C7H10F3N
Reinheit:95%+
Katalognummer:CM536708
Molekulargewicht:165.16

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Produkt-Details

CAS-Nr.:1780746-82-8
Molekulare Formel:C7H10F3N
Schmelzpunkt:-
SMILES-Code:FC(C1C2CCNCC12)(F)F
Dichte:
Katalognummer:CM536708
Molekulargewicht:165.16
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Bridged Compounds
Bridged ring compound refers to any two rings in the compound, which share two non-directly connected carbon atoms, and are classified into bicyclic hydrocarbons, tricyclic hydrocarbons, tetracyclic hydrocarbons, etc. Carbon atoms used in two or more rings are bridgehead carbon atoms, and the bond connecting the bridgehead carbon atoms is called a bridge. Bridged ring compounds are a class of organic compounds that are widely present in nature and usually have important physiological activities, such as the famous anticancer drug paclitaxel and antimalarial drug artemisinin.
bridged compounds,bridged bicyclic compounds
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Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.