Produktname:tert-Butyl 4-hydroxy-5-methyl-4-(trifluoromethyl)azepane-1-carboxylate

IUPAC Name:tert-butyl 4-hydroxy-5-methyl-4-(trifluoromethyl)azepane-1-carboxylate

CAS:1823815-32-2
Molekulare Formel:C13H22F3NO3
Reinheit:95%
Katalognummer:CM284894
Molekulargewicht:297.32

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Produkt-Details

CAS-Nr.:1823815-32-2
Molekulare Formel:C13H22F3NO3
Schmelzpunkt:-
SMILES-Code:O=C(N1CCC(C(F)(F)F)(O)C(C)CC1)OC(C)(C)C
Dichte:
Katalognummer:CM284894
Molekulargewicht:297.32
Siedepunkt:
Mdl-Nr.:MFCD28119199
Lagerung:

Category Infos

Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
Azepanes
The use of azepane as a scaffold for drug discovery remains of interest. The azepane linker is the key to efficient activity. A number of seven-membered ring derivatives have been prepared or investigated for their potential or actual pharmacological properties. Examples include azaalkane derivatives as PKB (protein kinase B) inhibitors.

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Product Other Information

Product Overview Tert-Butyl 4-hydroxy-5-methyl-4-(trifluoromethyl)azepane-1-carboxylate is known as Boc-aminocaproic acid, it has gained significant attention in the scientific community due to its potential applications in various fields, including medicinal chemistry, agricultural chemistry, and material science. 
Synthesis Method The synthesis of tert-Butyl 4-hydroxy-5-methyl-4-(trifluoromethyl)azepane-1-carboxylate involves the reaction of tert-butyl 4-hydroxy-5-methylazepane-1-carboxylate with trifluoromethyl iodide in the presence of a base, such as potassium carbonate. This reaction takes place under mild conditions and results in the formation of the desired product in good yields.
Chemical Properties It is ease of synthesis. Additionally, this compound has demonstrated potent biological activity, making it a promising candidate for further research.
Synthesis and Application Tert-Butyl 4-hydroxy-5-methyl-4-(trifluoromethyl)azepane-1-carboxylate has numerous applications in scientific research, particularly in medicinal chemistry. This compound has been shown to exhibit potent antitumor activity against various cancer cell lines, including breast, lung, and colon cancer. Additionally, it has been demonstrated to possess antibacterial and antifungal properties, making it a potential candidate for the development of new antibiotics.
Future Directions One potential avenue is the investigation of its potential as an anticancer agent in vivo. Another direction is the development of new antibiotics based on its antibacterial and antifungal properties. Additionally, the synthesis of analogs of this compound may lead to the discovery of new compounds with improved biological activity.