Produktname:quinoline-8-sulfonyl chloride

IUPAC Name:quinoline-8-sulfonyl chloride

CAS:18704-37-5
Molekulare Formel:C9H6ClNO2S
Reinheit:97%
Katalognummer:CM103571
Molekulargewicht:227.66

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Produkt-Details

CAS-Nr.:18704-37-5
Molekulare Formel:C9H6ClNO2S
Schmelzpunkt:-
SMILES-Code:ClS(=O)(=O)C1=CC=CC2=CC=CN=C12
Dichte:
Katalognummer:CM103571
Molekulargewicht:227.66
Siedepunkt:355.9°C at 760 mmHg
Mdl-Nr.:MFCD00006808
Lagerung:Keep in inert atmosphere, store at 2-8°C.

Category Infos

Quinolines
Quinolines are an important class of biologically active heterocyclic compounds, and their derivatives usually exhibit a variety of biological activities. They can be used as antimalarial drugs and in the preparation of other antimalarial drugs. Other important activities of quinoline derivatives include inhibitory activity against EGFR-TK and antipsychotic activity. Futhermore, quinoline scaffolds are present in various drug molecules, including the antimalarial drugs aablaquine, chloroquine, mefloquine and primaquine, and the antibacterial agents gatifloxacin, levofloxacin, and moxifloxacin.
Quinoline Price
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Column Infos

Mitapivat
Jan. 03 2024, Agios announces Phase 3 ENERGIZE study of PYRUKYND (Mitapivat) met primary endpoint and both key secondary endpoints in adults with non-transfusion-dependent(NTD) alpha- or beta-thalassemia. The positive data showed Mitapivat’s potential to become the first oral therapy approved for NTD thalassemia.
Mitapivat is a pyruvate kinase activator indicated for the treatment of hemolytic anemia in adults with pyruvate kinase (PK) deficiency in the US, and for the treatment of PK deficiency in adult patients in the EU. By activating and stabilizing mutant pyruvate kinase, Mitapivat targets the underlying enzymatic defect that causes chronic hemolysis and ineffective erythropoiesis in order to restore enzyme activity.

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