cas 1883301-82-3|| where to buy (1S)-2,2-difluorocyclopropanecarboxylic acid

Produktname:(1S)-2,2-difluorocyclopropanecarboxylic acid

IUPAC Name:(1S)-2,2-difluorocyclopropane-1-carboxylic acid

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CM326418-10g	in stock	ǲƤǠɐ

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: CAS-Nr.:1883301-82-3; Molekulare Formel:C4H4F2O2; Schmelzpunkt:-; SMILES-Code:O=C([C@H]1C(F)(F)C1)O; Dichte:

: Katalognummer:CM326418; Molekulargewicht:122.07; Siedepunkt:; Mdl-Nr.:MFCD30471588; Lagerung:Store at 2°C~8°C

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: Cyclopropanes; Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

: Fluorinated compounds; Fluorinated compounds refers to organic or inorganic compounds containing fluorine.

: Brepocitinib; Priovant Therapeutics announced positive Phase 2 NEPTUNE study results for brepocitinib in Non-Infectious Uveitis (NIU), showing strongest efficacy data in NIU observed to date. Brepocitinib selectively binds to and inhibits the activation of TYK2 and JAK1, thereby disrupting TYK2 and JAK-1-dependent cytokine signaling. This may reduce inflammatory responses and prevent inflammation-induced damage caused by certain immunological diseases.