Produktname:6-chloro-3-iodo-1H-pyrazolo[3,4-b]pyrazine

IUPAC Name:6-chloro-3-iodo-1H-pyrazolo[3,4-b]pyrazine

CAS:1935196-58-9
Molekulare Formel:C5H2ClIN4
Reinheit:95%+
Katalognummer:CM325847
Molekulargewicht:280.45

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Produkt-Details

CAS-Nr.:1935196-58-9
Molekulare Formel:C5H2ClIN4
Schmelzpunkt:-
SMILES-Code:IC1C2C(=NC(=CN=2)Cl)NN=1
Dichte:
Katalognummer:CM325847
Molekulargewicht:280.45
Siedepunkt:
Mdl-Nr.:MFCD26521481
Lagerung:Keep in a tight container and store at 2°C~8°C

Category Infos

Pyrazoles
Pyrazoles are organic compounds of the general formula C3H3N2H. It is a five-membered heterocycle consisting of three carbon atoms and two adjacent nitrogen atoms. As an H-bond-donating heterocycle, pyrazole has been used as a more lipophilic and metabolically more stable bioisomer of phenol. Pyrazoles have attracted more and more attention due to their broad spectrum of action and strong efficacy.
Pyrazone
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Pyrazines
Pyrazine is a heterocyclic aromatic organic compound with chemical formula C4H4N2. The marketed pyrazine drugs are mainly distributed in the field of anti-tumor and anti-infection. In recent years, there have been many new drugs in various fields, and there are some new target drugs worthy of attention.
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Column Infos

GDC-1971
Protein tyrosine phosphatase SHP2 mediates RAS-driven MAPK signaling and has emerged in recent years as a target of interest in oncology, both for treating with a single agent and in combination with a KRAS inhibitor. GDC-1971 (formerly RLY-1971) is a SHP2 inhibitor currently in clinical trials in combination with KRAS G12C inhibitor divarasib (GDC-6036) for the treatment of solid tumors driven by a KRAS G12C mutation.

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