Produktname:3-Chloro-4-(5-chloro-3-ethylimidazo[1,2-a]pyridin-2-yl)-1,2,5-thiadiazole

IUPAC Name:3-chloro-4-{5-chloro-3-ethylimidazo[1,2-a]pyridin-2-yl}-1,2,5-thiadiazole

CAS:1956370-94-7
Molekulare Formel:C11H8Cl2N4S
Reinheit:97%
Katalognummer:CM270695
Molekulargewicht:299.17

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Produkt-Details

CAS-Nr.:1956370-94-7
Molekulare Formel:C11H8Cl2N4S
Schmelzpunkt:-
SMILES-Code:CCC1=C(C2=NSN=C2Cl)N=C3C=CC=C(Cl)N31
Dichte:
Katalognummer:CM270695
Molekulargewicht:299.17
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Lagerung:

Category Infos

Imidazopyridines
With four imidazopyridine-containing drugs and one pyrazolopyridine-containing drug on the market, bicyclic pyridines containing ring-junction nitrogen are privileged structures in medicinal chemistry. With two nitrogen atoms with potential to serve as hydrogen bond acceptors, imidazopyridines and pyrazolopyridines may boost binding to target proteins and elevate potency. In addition, these structures have found utility in FBDD, covalent inhibitors, reducing metabolic liabilities, and creating novel chemical space and intellectual properties. With many of the advanced intermediates now commercially available, they will find more and more applications in drug discovery.
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Thiadiazoles
Thiadiazoles are a subfamily of azoles. Structurally, they are five-membered heterocyclic compounds containing two nitrogen atoms and one sulfur atom, and two double bonds, forming an aromatic ring. Depending on the relative positions of the heteroatoms, there are four possible structures; these forms do not interconvert and are therefore structural isomers rather than tautomers. These compounds themselves are rarely synthesized and have no particular utility, however, compounds that use them as structural motifs are fairly common in pharmacology.

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