Produktname:Methyl 2-[5-(hydroxymethyl)-3-methyl-1,2-oxazol-4-yl]benzoate
IUPAC Name:methyl 2-[5-(hydroxymethyl)-3-methyl-1,2-oxazol-4-yl]benzoate
- CAS：2086298-52-2
- Molekulare Formel：C13H13NO4
- Reinheit：95%
- Katalognummer：CM1074977
- Molekulargewicht：247.25
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Produkt-Details
- CAS-Nr.:2086298-52-2
- Molekulare Formel:C13H13NO4
- Schmelzpunkt:-
- SMILES-Code:O=C(OC)C=1C=CC=CC1C=2C(=NOC2CO)C
- Dichte:
- Katalognummer:CM1074977
- Molekulargewicht:247.25
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- Isoxazoles
- Isoxazole is a liquid heterocyclic compound C3H3NO isomeric with oxazole and having a penetrating odor like that of pyridine. Isoxazoles belong to an important class of five-membered aromatic heterocycles containing two electronegative heteroatoms, nitrogen and oxygen, in a 1,2-relationship and three regular sp2 carbon atoms. These molecules are found to be key components in various synthetic products in daily use and also present as a pharmacophore essential for biological activity in many drugs and bioactive natural products. In addition, isoxazoles have demonstrated their ability to exhibit hydrogen bond donor/acceptor interactions with a variety of enzymes and receptors.
Column Infos
- Pelabresib
- MorphoSys’ phase 3 study of Pelabresib in myelofibrosis demonstrates statistically significant improvement in spleen volume reduction and strong positive trend in symptom reduction.
Pelabresib (CPI-0610) is an investigational selective small molecule designed to promote anti-tumor activity by inhibiting the function of bromodomain and extra-terminal domain (BET) proteins to decrease the expression of abnormally expressed genes in cancer. MorphoSys intends to submit for approval in the U.S. and Europe in mid-2024.
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