Produktname:4-Azabicyclo[5.1.0]octane-8-carbonitrile

IUPAC Name:4-azabicyclo[5.1.0]octane-8-carbonitrile

CAS:2110391-37-0
Molekulare Formel:C8H12N2
Reinheit:95%+
Katalognummer:CM558048
Molekulargewicht:136.2

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Produkt-Details

CAS-Nr.:2110391-37-0
Molekulare Formel:C8H12N2
Schmelzpunkt:-
SMILES-Code:N#CC1C2CCNCCC12
Dichte:
Katalognummer:CM558048
Molekulargewicht:136.2
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

Bridged Compounds
Bridged ring compound refers to any two rings in the compound, which share two non-directly connected carbon atoms, and are classified into bicyclic hydrocarbons, tricyclic hydrocarbons, tetracyclic hydrocarbons, etc. Carbon atoms used in two or more rings are bridgehead carbon atoms, and the bond connecting the bridgehead carbon atoms is called a bridge. Bridged ring compounds are a class of organic compounds that are widely present in nature and usually have important physiological activities, such as the famous anticancer drug paclitaxel and antimalarial drug artemisinin.
bridged compounds,bridged bicyclic compounds
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Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.