Produktname:Mal-NH-ethyl-SS-propionic acid

IUPAC Name:3-({2-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]ethyl}disulfanyl)propanoic acid

CAS:2128735-24-8
Molekulare Formel:C12H16N2O5S2
Reinheit:95%+
Katalognummer:CM339014
Molekulargewicht:332.39

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Produkt-Details

CAS-Nr.:2128735-24-8
Molekulare Formel:C12H16N2O5S2
Schmelzpunkt:-
SMILES-Code:O=C(O)CCSSCCNC(CCN1C(C=CC1=O)=O)=O
Dichte:
Katalognummer:CM339014
Molekulargewicht:332.39
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
Cleavable linkers
Cleavable linkers rely on the inherent properties of a cell’s cytoplasmic compartments for selective release of the cytotoxic drug.
Maleimides
Thiol-maleimide is a bifunctional chemical compound that is commonly used in bioconjugation reactions to crosslink two molecules via the thiol (-SH) groups.
Disulfides/Thiols
In chemistry, a disulfide is a compound containing a R−S−S−R′ functional group or the S 2− anion. Thiols are the sulfur analogue of alcohols.
Carboxylic Acid
Carboxylic acid, any of a class of organic compounds in which a carbon (C) atom is bonded to an oxygen (O) atom by a double bond and to a hydroxyl group (―OH) by a single bond.

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