Produktname:3-[2-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]amino]ethoxy]propanoic acid
IUPAC Name:3-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethoxy)propanoic acid
- CAS:2139348-60-8
- Molekulare Formel:C18H19N3O7
- Reinheit:95%
- Katalognummer:CM1077431
- Molekulargewicht:389.36
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Produkt-Details
- CAS-Nr.:2139348-60-8
- Molekulare Formel:C18H19N3O7
- Schmelzpunkt:-
- SMILES-Code:OC(=O)CCOCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O
- Dichte:
- Katalognummer:CM1077431
- Molekulargewicht:389.36
- Siedepunkt:
- Mdl-Nr.:
- Lagerung:
Category Infos
- PROTAC-E3 Ligase Ligands
- Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
- PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.