Produktname:5-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]oxypentanoic acid

IUPAC Name:5-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}pentanoic acid

CAS:2169266-67-3
Molekulare Formel:C18H18N2O7
Reinheit:95%
Katalognummer:CM1077428
Molekulargewicht:374.35

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Produkt-Details

CAS-Nr.:2169266-67-3
Molekulare Formel:C18H18N2O7
Schmelzpunkt:-
SMILES-Code:OC(=O)CCCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1
Dichte:
Katalognummer:CM1077428
Molekulargewicht:374.35
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Mdl-Nr.:
Lagerung:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.

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