Produktname:tert-butyl N-[1-(6-bromo-3-chloroquinolin-4-yl)piperidin-4-yl]carbamate

IUPAC Name:tert-butyl N-[1-(6-bromo-3-chloroquinolin-4-yl)piperidin-4-yl]carbamate

CAS:2172875-14-6
Molekulare Formel:C19H23BrClN3O2
Reinheit:95%+
Katalognummer:CM1075011
Molekulargewicht:440.77

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Produkt-Details

CAS-Nr.:2172875-14-6
Molekulare Formel:C19H23BrClN3O2
Schmelzpunkt:-
SMILES-Code:CC(C)(C)OC(=O)NC1CCN(CC1)C1=C2C=C(Br)C=CC2=NC=C1Cl
Dichte:
Katalognummer:CM1075011
Molekulargewicht:440.77
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

Quinolines
Quinolines are an important class of biologically active heterocyclic compounds, and their derivatives usually exhibit a variety of biological activities. They can be used as antimalarial drugs and in the preparation of other antimalarial drugs. Other important activities of quinoline derivatives include inhibitory activity against EGFR-TK and antipsychotic activity. Futhermore, quinoline scaffolds are present in various drug molecules, including the antimalarial drugs aablaquine, chloroquine, mefloquine and primaquine, and the antibacterial agents gatifloxacin, levofloxacin, and moxifloxacin.
Quinoline Price
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Column Infos

Paltusotine
Crinetics’ once-daily oral paltusotine achieved the primary and all secondary endpoints in the phase 3 PATHFNDR-2 study in acromegaly patients.
Acromegaly is a serious rare disease generally caused by a pituitary adenoma, a benign tumor in the pituitary that secretes growth hormone (GH). Excess GH secretion causes excess secretion of IGF-1 from the liver. Prolonged exposure to increased levels of IGF-1 and GH leads to progressive and serious systemic complications, often resulting in bone, joint, cardiovascular, metabolic, cerebrovascular, or respiratory disease. 
Paltusotine is the first oral, once-daily selectively-targeted somatostatin receptor type 2 (SST2) agonist and is currently in investigational Phase 3 studies for acromegaly and a Phase 2 study for carcinoid syndrome.