Produktname:6-chloro-3-iodo-1-tetrahydropyran-2-yl-pyrazolo[3,4-b]pyrazine
IUPAC Name:6-chloro-3-iodo-1-(oxan-2-yl)-1H-pyrazolo[3,4-b]pyrazine
- CAS:2215028-64-9
- Molekulare Formel:C10H10ClIN4O
- Reinheit:95%+
- Katalognummer:CM479274
- Molekulargewicht:364.57
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Produkt-Details
- CAS-Nr.:2215028-64-9
- Molekulare Formel:C10H10ClIN4O
- Schmelzpunkt:-
- SMILES-Code:ClC1=CN=C2C(I)=NN(C3CCCCO3)C2=N1
- Dichte:
- Katalognummer:CM479274
- Molekulargewicht:364.57
- Siedepunkt:
- Mdl-Nr.:MFCD32220431
- Lagerung:
Category Infos
- Pyrazolopyrazines
- The pyrazolopyrazine ring system is a very interesting class of heterocyclic compounds considered as important scaffolds for many effective bioactive agents with low toxicity, antioxidant, anticonvulsant, antiparasitic, anti-inflammatory, antiviral, antibacterial, anti- Fungal and analgesic activity.
Column Infos
- GDC-1971
- Protein tyrosine phosphatase SHP2 mediates RAS-driven MAPK signaling and has emerged in recent years as a target of interest in oncology, both for treating with a single agent and in combination with a KRAS inhibitor. GDC-1971 (formerly RLY-1971) is a SHP2 inhibitor currently in clinical trials in combination with KRAS G12C inhibitor divarasib (GDC-6036) for the treatment of solid tumors driven by a KRAS G12C mutation.