Produktname:2-(2,6-dioxo-3-piperidyl)-5-prop-2-ynoxy-isoindoline-1,3-dione

IUPAC Name:2-(2,6-dioxopiperidin-3-yl)-5-(prop-2-yn-1-yloxy)-2,3-dihydro-1H-isoindole-1,3-dione

CAS:2226303-74-6
Molekulare Formel:C16H12N2O5
Reinheit:95%
Katalognummer:CM1077321
Molekulargewicht:312.28

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Produkt-Details

CAS-Nr.:2226303-74-6
Molekulare Formel:C16H12N2O5
Schmelzpunkt:-
SMILES-Code:O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C1C=CC(OCC#C)=C2
Dichte:
Katalognummer:CM1077321
Molekulargewicht:312.28
Siedepunkt:
Mdl-Nr.:
Lagerung:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.

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